Physeal involvement in chronic recurrent multifocal osteomyelitis |
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| Authors: | Dr D Manson D M Wilmot S King R M Laxer |
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| Institution: | (1) Department of Radiology, McMaster University, Hamilton, Ontario, Canada;(2) Present address: Department of Radiology, Associate of The Arthritis Society, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, Canada;(3) Department of Infectious Diseases, Associate of The Arthritis Society, The Hospital for Sick Children, Toronto, Ontario, Canada;(4) Division of Immunology, Department of Paediatrics, Associate of The Arthritis Society, The Hospital for Sick Children, Toronto, Ontario, Canada |
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| Abstract: | Chronic recurrent multifocal osteomyelitis is a recently recognized disease characterized by remissions and exacerbations of multiple bone lesions which radiographically and pathologically have the appearance of hematogenous osteomyelitis. No consistent etiology can be identified, and antimicrobial agents seem to have no beneficial effect. A review of the appearances of imaging modalities and the clinical and pathologic manifestations is undertaken in seven cases of CRMO. No therapeutic regimen resulted in consistent clinical or radiographic improvement. We suggest the sequelae of this process are not as benign as previously reported. |
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