正常腮腺64层螺旋CT灌注成像的初步研究

目的 应用64层螺旋CT灌注成像技术评价正常腮腺的血流动力学特点。方法 采用SIEMENS SOMATOM Sensation 64层螺旋CT 对37例正常腮腺进行CT灌注扫描，应用syngo body perfusion软件中Head/neck Tumor灌注模式进行数据后处理，分别测量正常腮腺、咬肌的血流量（BF）、patlak血容量（BV）、表面通透性（PS）的平均值及时间－密度曲线（TDC）形态。结果 37例正常腮腺的BF、BV和PS的平均值分别为（38.40±13.63）mL/100mL/min,（4.16±2.28）mL/100mL,（38.08±11.58）mL/100mL/min。同侧腮腺浅叶和深叶的同一灌注指标无明显差异；左、右侧腮腺的同一灌注指标无明显差异；正常腮腺与肌肉的同一灌注指标之间差异有显著性；正常腮腺灌注值与年龄之间无相关性。正常腮腺的TDC类型主要表现为缓升－缓降型。结论 CT灌注参数和时间－密度曲线可定量评价正常腮腺组织微循环的血流动力学变化，实现腮腺血流的定量研究。

The primary study of normal parotids with 64-slice CT perfusion imaging

【Abtract】Objective To evaluate the features of hemodynamics of normal parotids with 64-slice CT perfusion imaging. Methods 37 cases normal parotids were examined for CT perfusion. The perfusion data were transferred to a workstation running a commercial software (syngo body perfusion), with Head/neck Tumor perfusion mode. The mean BF, BV, PS and the shapes of TDC were measured. Results 37 cases normal parotids value of BF is measured as （38.40±13.63）ml/100ml/min, BV is （4.16±2.28）ml/100ml, PS is （38.08±11.58）ml/100ml/min. No difference of the same perfusion index was found in superficial and deep lobe of homonymy parotid；No difference of the same perfusion index was found in left and right side parotid. Significant different of the same perfusion index was found in normal parotids and muscles. No significant correlation was found in age and CT perfusion results of normal parotids. Shapes of TDC of 37 cases normal parotids were almost slow rise-slow drop type. Conclusion The parameters of CT perfusion and TDC curve can quantitatively evaluate microcirculatory hemodynamic change of naormal parotids, so quantitative study of blood flow of normal parotids come true.