| 心力衰竭患者血浆尾加压素的变化 |
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| 引用本文： | 周亚刚,张海婴,蒋克泉,伍旭升,张高峰,曹健敏. 心力衰竭患者血浆尾加压素的变化[J]. 蚌埠医学院学报, 2004, 29(4): 335-337 |
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| 作者姓名： | 周亚刚 张海婴 蒋克泉 伍旭升 张高峰 曹健敏 |
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| 作者单位： | 1. 上海市第五人民医院心内科, 200240;2. 上海市第五人民医院检验科, 200240;3. 上海市第五人民医院麻醉科, 200240 |
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| 摘 要： | 目的: 检测心力衰竭(心衰)患者血浆尾加压素(urotensinⅡ,UTN)的变化,探讨其在心衰中的临床意义。方法: 心衰组30例,NYHA心功能为Ⅱ~Ⅲ级;对照组19例,NYHA心功能分级Ⅰ级,采用放射免疫法测定血浆UTN.并作统计学分析。结果: 与对照组相比,UTN在治疗前心衰患者血浆中明显升高(P<0.01),并且不受年龄、性别、NYHA心功能分级和心脏疾病种类的影响(P>0.05)。结论: UTN是一个比较独立的危险因素,在心衰的诊断中有一定参考价值。
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| 关 键 词： | 心力衰竭 充血性 尾加压素 |
| 文章编号： | 1000-2200(2004)04-0335-03 |
| 收稿时间： | 2004-06-08 |
| 修稿时间： | 2004-06-08 |
Plasma level of urotensin in heart failure patients |
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| ZHOU Ya-gang,ZHANG Hai-ying,JIANG Ke-quan,WU Xu-sheng,ZHANG Gao-feng,CAO Jian-min. Plasma level of urotensin in heart failure patients[J]. Journal of Bengbu Medical College, 2004, 29(4): 335-337 |
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| Authors: | ZHOU Ya-gang ZHANG Hai-ying JIANG Ke-quan WU Xu-sheng ZHANG Gao-feng CAO Jian-min |
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| Affiliation: | Department of Cardiology, Shanghai Fifth People's Hospital, Affiliated to Fudan University, Shanghai 200240, China |
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| Abstract: | Objective: To investigate the change of plasma urotensin Ⅱ(UTN) levels in heart failure patients and its clinical significance.Methods: The UTN was measured in the plasma of 30 patients with heart failure(grade Ⅰ-Ⅲ by NYHA) and 19 controls(grade Ⅰ by NYHA),and the results were analyzed statistically.Results: The UTN was elevated in the plasma of heart failure patients(P<0.01) before treatment compared with that of the controls,and it was not related to the age,sex or heart function grade.Conclusions: Plasma UTN is a relatively independent risk factor,which is of use in the diagnosis of heart failure. |
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