保留灌肠在妇科肿瘤放疗中的疗效观察

目的:分析保留灌肠在妇科肿瘤盆腔放疗期间对放射性肠炎的治疗效果。方法:对77例妇科肿瘤患者资料进行回顾性分析。接受灌肠的36例患者为观察组;未接受灌肠的41例患者为对照组,在放疗期间仅口服思密达缓解出现的肠道症状。结果:观察组发生急性放射性肠炎7例,发生率19.44%(3例于1年左右出现肠出血);对照组发生急性放射性肠炎17例,发生率41.46%(11例于1～2年内出现肠出血、肠溃疡及直肠狭窄,发生率26.83%)。2组相比有显著性差异(P<0.05)。结论:在放疗期间行保留灌肠可减轻肠道反应,有助于病人顺利完成放射治疗;对放射所致的远期肠道损伤有重要的预防作用,对提高患者的生存质量有积极意义。

The Observation of Retention Enema on Radiation Enteritis in Radiotherapy of Gynecological Cancer

Objective:To analyze the therapeutic effect of retention enema on radiation enteritis in radiotherapy of gynecological cancer.Methods:Clinical data of 77 cases of gynecological cancer patients was analyzed retrospectively.All the patients were divided into two groups.In the treatment group,36 cases received retention enema.In the control group,41 cases took only smecta for relieving the symptoms,in the course of radiotherapy.Results:There were 7 cases(19.44%) of acute radiation enteritis occurred during radiotherapy,and 3 cases(8.33%) of chronic radiation enteritis occurred about one year after radiotherapy,in the treatment group.However,17 cases(41.46%) of acute radiation enteritis occurred during radiotherapy,and 11 cases(26.83%) of chronic radiation enteritis manifested as bleeding、ulcer and rectum stenosis occurred within one or two years,in the control group(P<0.05).Conclusion:Periodical retention enema is helpful to relieve intestinal reaction during radiotherapy for gynecological cancer.Moreover,it is beneficial for completion of radiotherapy and prevention of long-term intestinal radiation injury,and for improving the quality of life of gynecological cancer patients.