| 活检术前应用皮质醇对原发性中枢神经系统淋巴瘤病理诊断的影响 |
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| 引用本文： | 赵虎林,田增民,刘锐,王亚明,赵全军,于新,亓树彬,王福莉. 活检术前应用皮质醇对原发性中枢神经系统淋巴瘤病理诊断的影响[J]. 中国实验诊断学, 2011, 15(5): 828-829 |
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| 作者姓名： | 赵虎林 田增民 刘锐 王亚明 赵全军 于新 亓树彬 王福莉 |
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| 作者单位： | 海军总医院·全军神经外科中心,北京100048 |
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| 摘 要： | 目的研究活检术前应用皮质醇是否会影响原发性中枢神经系统淋巴瘤的病理诊断。方法回顾分析2005年2月至2011年2月期间73例经立体定向活检诊断为原发性中枢神经系统淋巴瘤患者的资料。结果 73例淋巴瘤患者中,39例（53.4%）在活检术前应用皮质醇;10例（73;13.7%）未得出阳性结果,再次行立体定向活检或开颅被证实为原发性中枢神经系统淋巴瘤,其中5例（39例）术前应用过皮质醇（12.8%）,5例（34例）未使用皮质醇（14.7%）（P=1.0）。结论活检术前应用皮质醇对大部分原发性中枢神经系统淋巴瘤患者而言不影响其病理诊断。
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| 关 键 词： | 原发性中枢神经系统淋巴瘤 皮质醇 活检术 病理诊断 影响 |
Effect of corticosteroid administration before biopsy on histopathological diagnosis of primary central nervous system lymphoma |
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| ZHAO Hu-lin,TIAN Zen-min,LIU Rui,et al.. Effect of corticosteroid administration before biopsy on histopathological diagnosis of primary central nervous system lymphoma[J]. Chinese Journal of Laboratory Diagnosis, 2011, 15(5): 828-829 |
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| Authors: | ZHAO Hu-lin TIAN Zen-min LIU Rui et al. |
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| Affiliation: | ZHAO Hu-lin,TIAN Zen-min,LIU Rui,et al.(Department of Neurosurgery,Navy General Hospital of People's Liberation Army,Beijing 100048,China) |
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| Abstract: | Objective To determine whether corticosteroid administration before biopsy prevents histopathological diagnosis of primary central nervous system lymphoma(PCNSL).Methods A retrospective review was performed of 73 PCNSL patients identified by stereotactic biopsy from Feb 2005 to Feb 2011.Results A total of 73 patients was identified.Thirty-nine patients(53.4%)received corticosteroids before diagnosis.Ten patients(of 73;13.7%) had undergone repeat stereotactic biopsy or craniotomy to confirm PCNSL.These inclu... |
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| Keywords: | primary central nervous system lymphoma corticosteroid Stereotactic biopsy histopathological diagnosis effect |
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