Lymphocyte interactions with endothelial cells. |
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| Authors: | Y Shimizu W Newman Y Tanaka S Shaw |
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| Affiliation: | Dept of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor 48109. |
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| Abstract: | Adhesion of lymphocytes to endothelium is vital to lymphocyte migration into lymphoid tissue and into inflammatory sites. In this review, Yoji Shimizu and colleagues identify the molecules that mediate lymphocyte-endothelial cell adhesion, describe the underlying principles of lymphocyte migration, and discuss a model of the sequence of events that allow a lymphocyte to successfully attach to endothelium and migrate into the surrounding tissue. |
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