基于Matlab精确测量分析耳蜗在颅底中的位置及其年龄趋势

为测量耳蜗在颅底的精确位置与蜗轴方位,并分析其在不同年龄组、侧别和性别中的差异,研究将46例正常人（92侧耳）的CT序列图像数据导入Mimics软件,读取蜗顶、蜗底中心点以及为确定以法兰克福平面为基准的标准空间坐标系的关键结构标志点的三维坐标,并基于Matlab软件编制计算程序LabyCalculation,确定标准空间坐标系的相关方程,计算蜗顶、蜗底中心点以及蜗轴在标准坐标系下的空间位置和方位,最后对数据进行统计分析.结果表明,耳蜗的位置与方位在不同年龄组、侧别和性别中具有一定差异.研究可为耳蜗发育研究提供形态数据,并对相关人工耳蜗手术提供依据和帮助.

Accurate Measurement of Cochlea's Position and Orientation in Skull Base and Analysis of Their Aging Trend Based on Matlab Software

In order to measure the cochlea ＇ s accurate position and the modiolus ＇ s orientation in skull base and to analyze their age, side and sex differences, CT serial images of 46 normal people（92 ears） were imported into Mimics software for image processing. Three-dimensional coordinate values of the cochlear cupula, the central point of the cochlear base and landmarks of key structures, which were used to define a standard three-dimensional coordinate system based on Frankfurt horizontal plane, were acquired. And then, the standard plane equations were approached by a self-developed calculation program, LabyCalculation, with the support of Matlab software. The spatial position of the cochlear cupula and cochlear base, and the spatial orientation of the modiolus in this new coordinate system were calculated. Finally, the data were analyzed statistically. The results show that cochlea ＇ s position and orientation in skull base have certain differences in different ages, sides and sexes. Our research can provide some help for ear development study and the cochlear implantation.