| 瞬时弹性扫描仪测定中国人慢性乙型肝炎患者肝脏硬度的影响因素分析 |
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| 引用本文： | 李冰,张健,韩萍,邵清,纪冬,陈国凤. 瞬时弹性扫描仪测定中国人慢性乙型肝炎患者肝脏硬度的影响因素分析[J]. 中国实验诊断学, 2011, 15(12): 2061-2063 |
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| 作者姓名： | 李冰 张健 韩萍 邵清 纪冬 陈国凤 |
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| 作者单位： | 解放军第302医院,肝纤维化无创诊疗中心,北京100039 |
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| 基金项目： | 第302医院院内基金(YNKT2009006) |
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| 摘 要： | 目的观察瞬时弹性扫描仪测定中国慢性乙型肝炎病人硬度值的影响因素。方法对110例中国慢性乙型肝炎患者应用瞬时弹性扫描仪进行检测,根据ALT情况分为3组,观察肝弹性值及各个血清学指标有无明显差异。结果经统计学检查,三组患者在年龄、性别方面无显著差异;A、B、C三组在肝弹性值、ALT、AST、TBIL水平上均有明显差异,A、B两组与C在ALP指标上均有明显差异,而三组在GGT及PLT水平检测未见明显差异。三组分别进行前后两次成组比较,发现A组在所关注的指标中均无差异。B组在肝弹性值、ALT、AST指标有所差异。C组在肝弹性值、ALT、AST、TBIL指标有所差异。B、C两组LSM与ALT呈显著相关性。随ALT下降此2组LSM绝大部分逐渐降至肝硬化界值17KPa以下。结论当患者ALT升高程度在2倍以上时肝弹性值会受到影响,在10倍以上升高时影响更为明显。当ALT明显升高时,动态观察LSM会更准确的判定肝纤维化的程度。
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| 关 键 词： | 瞬时弹性扫描仪 肝纤维化 血清学指标 |
The influencing factors of testing liver fibrosis by Fibroscan in chronic hepatitis B patients |
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| LI Bing,ZHANG Jian,HAN Ping,et al.. The influencing factors of testing liver fibrosis by Fibroscan in chronic hepatitis B patients[J]. Chinese Journal of Laboratory Diagnosis, 2011, 15(12): 2061-2063 |
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| Authors: | LI Bing ZHANG Jian HAN Ping et al. |
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| Affiliation: | LI Bing,ZHANG Jian,HAN Ping,et al.(The302 Hospital of PLA,Beijing 100039,China) |
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| Abstract: | Objective Methods To observe the factors which will influcence the results of testing liver fibrosis by Fibroscan in Chinese chronic hepatitis B patients.Methods 110 cases of hepatitis B patients were divided into 3 groups according to the level of ALT.There were no difference among 3 groups in age and sex.Results TbiL and Fitness targets were significantly different between A group,B group and C group.ALP target was significantly different between A group and C group,the same as B group and C group.The tar... |
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| Keywords: | Fibroscan Fibrosis Serum marker |
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