冠心病患者颈动脉粥样硬化与冠状动脉粥样硬化的相关性分析

目的对冠心病患者颈动脉粥样硬化与冠状动脉硬化之间的关系进行探讨。方法共收集患者246例,以冠状动脉造影的结果为依据将所有的患者分组,其中冠心病组176例,非冠心病组70例;将冠心病组患者再次分组,其中单支病变组69例,双支病变组56例,三支病变组51例,比较冠心病组及非冠心病组间及不同的冠状动脉病变支数的三组间的IMT、斑块积分及Gensini评分;分析冠状动脉病变支数与以上观察指标的相关性。结果冠心病组与非冠心病组比较具有较高的颈动脉IMT、斑块积分及Gensini评分(P<0.05);与单支病变组比较,双支病变组及三支病变组患者具有较高的颈动脉斑块发生率、颈动脉IMT、斑块积分及Gensini评分(P<0.05);冠状动脉病变支数与IMT、颈动脉斑块积分呈显著正相关,Gensini评分与IMT及颈动脉斑块积分呈显著正相关(P<0.05)。结论冠状动脉的粥样硬化程度随着患者的颈动脉粥样硬化程度的升高而加重,冠心病的严重程度可以通过超声检测反映出来。

Correlation of carotid atherosclerosis and coronary atherosclerosis in patients with coronary heart disease

Objective To explore the correlation of carotid atherosclerosis and coronary atherosclerosis in patients with coronary heart disease. Methods A total of 246 cases were selected, they were divided into groups on the bases of the re- sults of coronary angiography, there were 176 cases in coronary heart disease group, 70 cases in non-coronary heart disease group; the coronary heart disease group was divided into single-vessel disease group （n = 69）, double vessel disease group （n = 56）, three lesion group （n = 51）; compared IMT, plaque score and Gensini score between coronary heart disease group and non-coronary heart disease group, among the number of different coronary arteries; analyzed the correlation of coronary artery lesions with the above observation indicators. Results Coronary heart disease group compared non-coronary heart disease group had higher carotid IMT and plaque score and Gensini score （P 〈 0.05）; compared with single-vessel disease, double vessel disease group and three lesionspatients had higher incidence of carotid artery plaque, carotid IMT and plaque score and Gensini score （P 〈 0.05）; coronary artery lesions IMT, carotid plaque score showed a significant positive correla- tion, while the Gensiniscore and IMT and carotid plaque score showed a significant positive correlation （P 〈 0.05）. Conclu- sion Coronary atherosclcrosis with increasing in patients with carotid atherosclerosis degree aggravate the severity of coro- nary heart disease can be detected by ultrasound reflected.