多囊卵巢综合征患者的内分泌和代谢特点分析及与体质量的相关性研究

目的探讨多囊卵巢综合征患者的内分泌和代谢特点，并对其与体质量的相关性进行分析。方法选取来我院治疗的多囊卵巢综合征患者93例，分为肥胖组（n：55），非肥胖组（n=38），所有患者均检测LH、FSH、PRL、E2、T及胰岛素、A2、FPG，使用Spearman相关性分析各观察指标与体质量的相关性。结果与非肥胖组比较，肥胖组具有较低的FSH、E2，具有较高的BMI、LH、PRL、T、A2、IR，差异均具有统计学意义（P〈0．05）。肥胖组与非肥胖组比较具有较高的空腹胰岛素水平，差异有统计学意义（P〈0．05）。结论高雄激素血症在肥胖的多囊卵巢综合征患者中出现的可能性更大．具有更为严重的胰岛素抵抗。

Analysis of endocrine and metabolic characteristics and correlation with body mass in polycystic ovary syndrome patients

Objective To explore characteristics of endocrine and metabolic with polycystic ovary syndrome and analyze the correlation with body mass. Methods A total of 93 cases with polycystic ovary syndrome were selected in our hospital and were divided into two groups, there were 55 cases in obese group and 38 case in non-obese group. LH, FSH, PRL, E2, T and insulin, A2, FPG of all the objects were detected, we used Spearman correlation analysis to observe the correlation be- tween the body mass and all the indexes. Results The obese group compared with non-obese group had lower FSH,E2 and higher BMI, LH, PRL, T, A2 and IR. There were significant differences in all the indexes above between two groups （P 〈 0.05）. The obese group compared with non-obese group had higher fasting insulin levels with significant difference （P 〈 0.05）. Conclusion Hyperandrogenism in obese patients with polycystic ovary syndrome are more likely to have more severe insulin resistance