| 清火护肝颗粒对实验性肝炎保护作用的研究 |
| |
| 引用本文： | 高勇,胡宗卫,齐建. 清火护肝颗粒对实验性肝炎保护作用的研究[J]. 实用中医内科杂志, 2010, 24(1): 40-41. DOI: 10.3969/j.issn.1671-7813.2010.01.18 |
| |
| 作者姓名： | 高勇 胡宗卫 齐建 |
| |
| 作者单位： | 辽宁省大连市中医医院,辽宁大连,116013 |
| |
| 摘 要： | [目的]观察清火护肝颗粒的抗实验性肝炎作用。[方法]分别采用四氮化碳(CCl_4)和D-半乳糖胺(D-GalN)诱导小鼠发生实验性急性肝损伤。[结果]清火护肝颗粒可对抗四氮化碳和D-半乳糖胺所致血清中ALT、AST、ALP升高及GSH降低,并减轻D-半乳糖胺所致肝脏病变程度,其中以中剂量(相当于生药80g/Kg)预防给药7d效果最佳。[结论]清火护肝颗粒对实验性肝炎有保护作用。
|
| 关 键 词： | 实验性肝炎 清火护肝颗粒 D-半乳糖胺 四氯化碳 |
Protective effects of Yangganqingrekeli on experimental hepatitis |
| |
| GAO Yong,HU Zong-wei,QI Jian. Protective effects of Yangganqingrekeli on experimental hepatitis[J]. , 2010, 24(1): 40-41. DOI: 10.3969/j.issn.1671-7813.2010.01.18 |
| |
| Authors: | GAO Yong HU Zong-wei QI Jian |
| |
| Affiliation: | (Dalian Chinese Medicine Hospital, Dalian 116013, Liaoning, China) |
| |
| Abstract: | [ Objective ] To study the protective effects of Yangganqingrekeli on experimental hepatitis. [ Method] Mice acute liver injury model was induced by CCl4or D - galactosamine （ D - GL）. [ Result] The decrease of ALT, AST, ALP, and the increase of GSH inserum which were induced by CCl4 or D - GL could be resisted by Yangganqingrekeli, the hepato - cellular degeneration and necrosis induced by D - GL could also be diminished. The best dosage is （80g .kg^-1/d,7d, ig）. [ Couclusion] Pretreatment with Yangganqingrekeli moderately prevents the liver damage induced by CCl4 or D - GL. |
| |
| Keywords: | experimental hepatitis Yangganqingrekeli CCl4 d - galactosamine |
| 本文献已被 维普 万方数据 等数据库收录！ |
|
