| 车间空气中乙酰甲胺磷卫生标准研究 |
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| 引用本文： | 陈秀凤 吴立仁 等. 车间空气中乙酰甲胺磷卫生标准研究[J]. 环境与职业医学, 2001, 18(2): 78-80 |
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| 作者姓名： | 陈秀凤 吴立仁 等 |
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| 作者单位： | 浙江省医学科学院!杭州310013(陈秀凤，吴立仁，吴加罗，吴晓东，俞永旦)，绍兴市卫生防疫站(曹婉娟) |
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| 基金项目： | 卫生部卫生标准“八五”规划项目 (编号 :3 92 0 85) |
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| 摘 要： | 目的 研制车间空气中乙酰甲胺磷的国家卫生标准。方法 乙酰甲胺磷动物毒性试验及接触工人的职业流行病学调查。结果 乙酰甲胺磷大鼠经口LD50为823mg/kg。致突变性试验、致畸试验及迟发性神经毒性试验均为阴性。车间空气中乙酰甲胺磷浓度测定大多数在0．5mg/m^3以下。未发现接触工人有中毒症状。结论 建议车间空气中乙酰甲胺磷的最高容许浓度为0．5mg/m^3，其时间加权平均容许浓度为0．3mg/m^3。
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| 关 键 词： | 乙酰甲胺磷 毒理 最高容许浓度 时间加权平均容许浓度 卫生标准 车间空气 |
| 文章编号： | 1006-3617(2001)02-0078-03 |
| 修稿时间： | 2001-01-28 |
Study on the Health Standard for Acephate in the Air of Workplace |
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| CHEN Xiu feng ,WU Li ren ,WU Jia luo ,WU Xiao dong ,CAO Wen juan ,YU Yong dan. Study on the Health Standard for Acephate in the Air of Workplace[J]. Journal of Environmental & Occupational Medicine, 2001, 18(2): 78-80 |
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| Authors: | CHEN Xiu feng WU Li ren WU Jia luo WU Xiao dong CAO Wen juan YU Yong dan |
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| Affiliation: | CHEN Xiu feng 1,WU Li ren 1,WU Jia luo 1,WU Xiao dong 1,CAO Wen juan 2,YU Yong dan 1 |
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| Abstract: | Objective] To establish national health standard for acephate in the air of workplace.[Method]Occupational epidemiological investigation in field and animal experiments were performed to study the toxicity of acephate. [Results] LD 50 for acephate by intragastric administration is 823 mg/kg in rats. Negative effects were obtained in experimental assays of mutagenicity,teratogenicity and delayed neurotoxicity.The results of determination showed that most of the acephate concentrations in the air of workplaces were below 0 5 mg/m 3.The signs of adverse effects of acephate poisoning in workers were not fuond. [Conclusion] The maximum allowable concentration(MAC) and the time weighted average allowable concentration(TWA AC) were recommended as 0 5 mg/m 3 and 0 3 mg/m 3,respectively. |
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| Keywords: | acephate toxicology MAC TWA exposure limit |
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