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Expression pattern of testis-specific expressed gene 2 in cryptorchidism model and its role in apoptosis of spermatogenic cells
Authors:Tao Hu  Zhiyu Wang  Fuqing Zeng  Xiaochun Chen  Zhaohui Gu  Liduan Zheng  Qiangsong Tong
Institution:Department of Urology Union Hospital Tongji Medical College Huazhong University of Science and Technology Department of Pathology Department of Pediatric Surgery
Abstract:In our previous study,we identified a novel testis-specific expressed gene 2(TSEG-2) from mouse testis.To further investigate its functions,35 male Balb/c mice(8 weeks old) were divided into cryptorchidism group(n=20),sham group(n=10),and control group(n=5).In cryptorchidism group,the right testes were anchored to the inner lateral abdominal wall.In situ hybridization(ISH) was applied to measure the localization of TSEG-2 in mouse testis.Real-time quantitative PCR was performed to detect the expression of T...
Keywords:animal model  testis-specific expressed gene 2  polyethylenimine  apoptosis  
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