葡萄糖调节受损干预治疗进展

葡萄糖调节受损（IGR）干预治疗的是当今糖尿病预防的循证医学研究热点。目前，证实干预IGR能降低2型糖尿病发病危险的研究有中国大庆研究、多国STOP—NIDDM研究、美国DPP研究、瑞典Malmo研究、芬兰DPS研究、TRIPOD研究、ORIGIN研究、DREAM研究、NAVIGATOR研究等。主要的干预方法是饮食控制、运动锻炼等强化生活方式改变；药物干预，主要药物：阿卡波糖、二甲双胍、罗格列酮、雷米普利等；中医中药干预。本文就葡萄糖调节受损干预治疗现状作一综述。

Advances in Intervention Therapy on the Impaired Glucose Regulation

The Impaired Glucose Regulation （IGR） interference therapy is nowdays the key issue on Evidence - Based Medicine study for Diabetes. Prevention. Actually, sereis of studies has proved that the interference therapy is able to reduce the risk factors of Diabetes Mellitus type Ⅱ and those underlining studies are： Chinese Da Qing study （大庆）, the muhinations Stop - NIDDM study, The U. S. DPP study, Sweden Malmo study, Finland DPS study, TRIPOD study, ORIGIN study, DREAM study and NAVIGATOR study etc. In one hand, the major methods used in this research are Diet Control and Sport activities from which emphasize on the way of life habits changes. In another hand, medications interference as method has been taken into consideration and the most used are ： Dimethyldiguanide （ mefformine）, acarbose, rosiglitazone, ramipril etc. This article on The Impaired Glucose Regulation （IGR） interference therapy is just a referential summary.