| 胆道梗阻后炎症反应发生的过程及机制 |
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| 引用本文： | 易杰明 综述 关养时 审校. 胆道梗阻后炎症反应发生的过程及机制[J]. 中国普通外科杂志, 2012, 21(5): 607-610 |
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| 作者姓名： | 易杰明 综述 关养时 审校 |
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| 作者单位： | 广东医学院肝胆外科;深圳市罗湖区人民医院普通外科 |
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| 摘 要： | 胆道梗阻(biliary obstruction)的病因非常复杂,但胆道梗阻后产生的一系列病理生理变化却大致相同,炎症反应作为其中的主要变化在胆道梗阻后造成的肝脏及机体损伤中起着十分重要的作用。了解并理清炎症反应在胆道梗阻后的病理生理变化中的作用及影响对认识这个疾病有着特别的意义。笔者就胆道梗阻后炎症反应产生的过程及机制予以综述。
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| 关 键 词： | 胆汁淤积 炎症 内毒素血症 综述文献 |
| 收稿时间： | 2011-09-28 |
| 修稿时间： | 2012-04-12 |
Process and mechanism of inflammatory response following biliary obstruction |
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| YI Jieming,GUAN Yangshi. Process and mechanism of inflammatory response following biliary obstruction[J]. Chinese Journal of General Surgery, 2012, 21(5): 607-610 |
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| Authors: | YI Jieming GUAN Yangshi |
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| Affiliation: | 1.Department of Hepatobiliary Surgery,Guangdong Medical college,Zhanjiang,Guangdong 524000 China;2.Guangdong Medical College,Zhanjiang,Guangdong 524000 2.Department of General Surgery,Shenzhen Luohu People’s Hospital,Shenzhen,Gaungdong 518001,China) |
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| Abstract: | The causes of biliary obstruction are diverse,but the subsequent series of pathophysiological alterations are quite similar after its onset.Inflammatory response as the main reaction plays a very important role in the hepatic and systemic injury secondary to biliary obstruction.To understand and clarify the role and impact of the inflammatory response in the pathophysiological alterations following biliary obstruction is of special significance for dealing with this disease.This paper reviews the process of the inflammatory response to biliary obstruction and its underlying mechanism. |
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| Keywords: | Cholestasis Inflammation Endotoxemia Review |
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