| 进展期非小细胞肺癌的维持治疗 |
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| 引用本文： | 罗吕宏,范云. 进展期非小细胞肺癌的维持治疗[J]. 国际肿瘤学杂志, 2009, 36(3). DOI: 10.3760/cma.j.issn.1673-422X.2009.03.015 |
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| 作者姓名： | 罗吕宏 范云 |
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| 作者单位： | 浙江省肿瘤医院化疗中心,杭州,310022 |
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| 摘 要： | 4～6周期联合化疗达到"化疗疗效平台"后,进一步维持治疗能否改善进展期非小细胞肺癌患者的生存,是目前临床关注的热点.随着一些具有良好耐受性的化疗药物和分子靶向药物的介入,一些临床研究已经证实,在疾病控制的患者,维持治疗能带来进一步的临床获益,主要表现为无进展生存期的延长,并有改善总生存的趋势.
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| 关 键 词： | 癌 非小细胞肺 药物疗法 维持治疗 |
Maintenance therapy in advanced non-small cell lung cancer |
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| Abstract: | Following four to six cycles of chemotherapy for patients with non-small cell lung cancer ( NSCLC). Chemotherapy efficacy plateau has been achieved. Whether maintenance therapy can improve these patient' s survival becomes a new focus now. Several randomized clinical trials have demonstrated that mainte-nance therapy with well-tolerated chemotherapeutic or molecular-targeted agents may benefit patients with ad-vanced NSCLC who experience a response or disease stabilization after chemotherapy, which include prolonging progression-free survival and attering total survival. |
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| Keywords: | Carcinoma,non-small-cell lung Drug therapy Maintenance therapy |
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