Photodynamic therapy for Barrett''s oesophagus: How I do it |
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Authors: | J. Andrew C. Thorpe FRCS MB ChB |
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Affiliation: | aYorkshire Laser Centre, UK;bSt James's University Hospital, First Floor, Lincoln Wing, Beckett Street, Leeds LS9 7TF, UK |
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Abstract: | Endoscopic photodynamic therapy (PDT) for Barrett's oesophagus with high-grade dysplasia or early carcinoma is undertaken after full investigation. Endoscopic assessment is mandatory to determine the extent of the Barrett's segment and neoplastic changes. Photofrin at 2 mg/kg bw is used, followed 24–72 h later by illumination of 630 nm light, 200 J/cm of lesion. The whole of the Barrett's segment should be exposed to illumination. Patients are followed up endoscopically at 3 months. |
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Keywords: | Photodynamic therapy Barrett's oesophagus |
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