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鼻咽癌放射治疗后颈部淋巴结复发原因分析
引用本文:顾文栋,冯炎.鼻咽癌放射治疗后颈部淋巴结复发原因分析[J].中华肿瘤防治杂志,2004,11(5):518-520.
作者姓名:顾文栋  冯炎
作者单位:复旦大学附属肿瘤医院放射治疗科,上海,200032
摘    要:目的 :探讨鼻咽癌放射治疗后颈部淋巴结复发原因及其特点。方法 :回顾性分析了 1994年 11月~ 2 0 0 1年 9月因鼻咽癌放射治疗后颈部淋巴结复发而行颈淋巴结清除的 69例患者的临床资料。结果 :鼻咽癌放疗后颈部淋巴结复发时间平均为 3 4 5个月( 6 5~ 2 42 5个月 ) ,其与治疗前N分期和照射剂量相关 ,联合化疗不能提高颈部淋巴结的控制率。结论 :鼻咽癌放疗后颈部淋巴结复发大多发生在 2年内 ,早期诊断和提高颈部照射剂量有可能提高颈部控制率 ,而联合化疗无效

关 键 词:鼻咽肿瘤/放射疗法  辐射剂量  复发    淋巴结
文章编号:1009-4571(2004)05-0518-03
修稿时间:2003年1月3日

Analysis of cervical lymph nodes recurrence after radiotherapy for nasopharyngeal carcinoma
GU Wen-dong,FENG Yan.Analysis of cervical lymph nodes recurrence after radiotherapy for nasopharyngeal carcinoma[J].Chinese Journal of Cancer Prevention and Treatment,2004,11(5):518-520.
Authors:GU Wen-dong  FENG Yan
Institution:GU Wen-dong,FENG Yan Department of Radiation Oncology,Cancer Hospital,Fudan University,Shanghai 200032,P.R.China
Abstract:OBJECTIVE:To analyze the reasons and characteristics of lymph nodes recurrence after radiotherapy for nasopharyngeal carcinoma.METHODS:From November 1994 to September 2001,sixty-nine patients received neck dissection due to lymph nodes recurrence after definitive radiotherapy.Retrospective analysis was performed.RESULTS:The mean interval between the end of radiotherapy and surgery was 34.5 months(6.5-242.5 months).N stage and the radiation dose were significantly prognostic factors in the statistic analysis.CONCLUSIONS:Most of the recurrence occurres in the first two years.Early diagnosis and higher radiation dose may increase control rate of cervical lymph nodes.
Keywords:nasopharyngeal neoplasms/radiotherapy  radiation dosage  recurrence  neck  lymph nodes
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