Rothia dentocariosa sepsis in a pediatric renal transplant recipient having post-transplant lymphoproliferative disorders |
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Authors: | Wiesmayr Silke Stelzmueller Ingrid Berger Natalie Jungraithmayr Therese C Fille Manfred Eller Miriam Zimmerhackl Lothar Bernd Margreiter Raimund Bonatti Hugo |
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Institution: | Department of Pediatrics, Medical University, Innsbruck, Austria. |
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Abstract: | BACKGROUND: Rothia dentocariosa (RD) is a Gram-positive rod that colonizes the human oral cavity and can cause infective endocarditis. RESULT: We report on a six-yr-old boy who underwent renal transplantation for polycystic kidney disease at the age of eight months. He developed post-transplant lymphoproliferative disorders after four yr and progressive graft failure. Following chemotherapy, the patient presented with neutropenia and sepsis. RD was isolated from blood and treatment with piperacillin/tazobactam was initiated; however, the child died because of multiorgan failure. DISCUSSION: To the best of our knowledge, this is the first case of RD sepsis in a pediatric solid organ transplant recipient. |
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Keywords: | immunosuppression lethal sepsis pediatric transplant recipient PTLD Rothia dentocariosa |
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