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Timing of surgery in Crohn's disease: A key issue in the management
引用本文:Alós R,Hinojosa J.Timing of surgery in Crohn's disease: A key issue in the management[J].世界胃肠病学杂志(英文版),2008,14(36):5532-5539.
作者姓名:Alós R  Hinojosa J
作者单位:[1]Servicio de Cirugia General, Unidad de Coloproctologia, Hospital de Sagunto, Valencia, Spain; [2]Unidad de Digestivo, Servicio de Medicina Interna, Hospital de Sagunto, Valencia, Spain
摘    要:The timing of the decision for operation in Crohn's disease is based on an evaluation of the several factors such as the failure of medical treatment, complications due to the Crohn's disease or to the farmacological therapy, development of dysplasia or cancer and growth retardation. A complete evaluation of these factors should result in operation timed to the patient's best advantage, achieving maximal relief of symptoms with improvement of quality of life. Given the complexity and heterogeneity of the disease and the different options for treatment, is difficult to systematize when the optimal moment for the surgery is arrived. A very important factor in the management of Crohn's disease is the multidisciplinary approach and the patient preference should be a significant factor in determining the choice of therapy. The surgery should be considered such another option in the sequential treatment of Crohn's disease. We have analyzed the factors that are involved in the decision taking of the surgical treatment regarding to the experience and the published literature. When did the medical therapy fail? when is the appropriate moment to operate on the patient? Or which complications of Crohn's disease need a surgery? These are some of the questions we will try to answer.

关 键 词:克罗恩氏病  节段性回肠炎  外科治疗  药物治疗
收稿时间:2008 Aug 18

Timing of surgery in Crohn's disease: a key issue in the management
Alós Rafael,Hinojosa Joaquín.Timing of surgery in Crohn's disease: a key issue in the management[J].World Journal of Gastroenterology,2008,14(36):5532-5539.
Authors:Alós Rafael  Hinojosa Joaquín
Institution:1. Servicio de Cirugia General,Unidad de Colopro ctologia,Hospital de Sagunto,Valencia,Spain
2. Unidad de Digestivo,Servicio de Mcdicna Interna,Hospital de Sagunto,Valencia,Spain
Abstract:The timing of the decision for operation in Crohn’s disease is based on an evaluation of the several factors such as the failure of medical treatment, complications due to the Crohn’s disease or to the farmacological therapy, development of dysplasia or cancer and growth retardation. A complete evaluation of these factors should result in operation timed to the patient’s best advantage, achieving maximal relief of symptoms with improvement of quality of life. Given the complexity and heterogeneity of the disease and the different options for treatment, is difficult to systematize when the optimal moment for the surgery is arrived. A very important factor in the management of Crohn’s disease is the multidisciplinary approach and the patient preference should be a significant factor in determining the choice of therapy. The surgery should be considered such another option in the sequential treatment of Crohn’s disease. We have analyzed the factors that are involved in the decision taking of the surgical treatment regarding to the experience and the published literature. When did the medical therapy fail? when is the appropriate moment to operate on the patient? Or which complications of Crohn’s disease need a surgery? These are some of the questions we will try to answer.
Keywords:Crohn's disease  Surgical treatment  Hedi cal therapy
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