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表皮生长因子与膀胱肿瘤关系的探讨
引用本文:阮翘 王瑞. 表皮生长因子与膀胱肿瘤关系的探讨[J]. 河南医学研究, 1996, 5(3): 221-222
作者姓名:阮翘 王瑞
作者单位:河南医科大学第一附属医院核医学科,河南医科大学第一附属医院泌尿外科,郑州铁路局中心医院核医学科
摘    要:采用放射免疫分析法测定了35例正常人群和30例膀胱肿瘤患者尿中表皮生长因子(EGF)水平,结果显示:膀胱肿瘤患者尿中表皮生长因子水平明显低于正常人群,P<0.05。提示:EGF参与膀胱肿瘤细胞的代谢,对肿瘤细胞的生长起促进作用,尿中EGF水平降低可能与EGF在膀胱肿瘤细胞内降解有关。

关 键 词:膀胱肿瘤,表皮生长因子,放射免疫分析

RELATION OF EPIDERMAL GROWTH FACTOR(EGF)WITH HUMAN BLADDER TUMOR
Ruan Qiao,Wang Rui,Xi Rui,et al. RELATION OF EPIDERMAL GROWTH FACTOR(EGF)WITH HUMAN BLADDER TUMOR[J]. Henan Medical Research, 1996, 5(3): 221-222
Authors:Ruan Qiao  Wang Rui  Xi Rui  et al
Abstract:The EGF Ievels of urine from 35 cases of normal human beings and 30 patientswithbbdder tumor were determined by radioimmunoassay.The EGF levels in urine from normalcontrols were higher than that from patients with bladder tumor.The difference was significant(P< 0.05).The result indicated that EGF tcok part in the metabolism of the bladder tumor andpromoted tumor growth.EGF might be discomposed in tumor cell and its level in urine was re-duced.
Keywords:epidermal growth factor  bladder tumor   radioimmunoassay
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