| 肿瘤浸润淋巴细胞治疗老年人恶性胸水的疗效分析 |
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| 引用本文： | 蒋敬亭,吴昌平,陈雪勤. 肿瘤浸润淋巴细胞治疗老年人恶性胸水的疗效分析[J]. 中华老年医学杂志, 1999, 18(1): 35-37 |
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| 作者姓名： | 蒋敬亭 吴昌平 陈雪勤 |
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| 作者单位： | 苏州医学院附属第三医院肿瘤生物诊疗中心 |
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| 基金项目： | 江苏省社会发展科技指导性计划 |
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| 摘 要： | 目的探讨肿瘤浸润淋巴细胞（ＴＩＬ）治疗老年癌症患者恶性胸水的有效率。方法应用癌症患者自体胸水的ＴＩＬ培养、扩增后产物经胸腔内输注治疗２１例老年人恶性胸水，每隔日１次，至少４次。结果２１例经治疗后，胸水中淋巴细胞增加，肿瘤细胞逐渐减少，胸腔积液逐渐吸收，１个月后１９例达完全缓解和部分缓解，有效率为９０．５％。结论自体胸水ＴＩＬ可治疗恶性胸水，同时可提高老年癌症患者的免疫功能，对机体无毒副作用。
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| 关 键 词： | 胸腔积液.恶性 淋巴细胞.肿瘤浸润 |
An analysis of the therapeutic effect of tumour infiltrating lymphocytes on malignant pleural effusion in aged |
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| JIANG Jingting,WU Changping,CHEN Xueqin,et al.. An analysis of the therapeutic effect of tumour infiltrating lymphocytes on malignant pleural effusion in aged[J]. Chinese Journal of Geriatrics, 1999, 18(1): 35-37 |
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| Authors: | JIANG Jingting WU Changping CHEN Xueqin et al. |
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| Affiliation: | JIANG Jingting,WU Changping,CHEN Xueqin,et al.The Third Affiliated Hospital of Suzhou Medical College,Changzhou 213003 |
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| Abstract: | Objective To study the therapeutic effect of tumour infiltrating lymphocytes (TIL) on malignant pleural effusion in aged cancer patients. Methods TIL cultured and amplified product of cancer patient's own malignant pleural effusion was used for treatment in aged cancer patients by intrapleural injection once every other day for at least four times. Results In 21 cases treated, lymphocytes in pleural effusion increased, while tumour cells gradually decreased, and pleural effusion gradually absorbed. After 1 month 19 cases were effective (90 5%). Conclusions Auto pleural effusion tumour infiltrating lymphocytes might be effective for malignant pleural effusion. |
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| Keywords: | Pleural effusion malignant Lymphocytes tumour infiltrating |
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