白癜风826例临床分析

对1998年至2008年我院白癜风门诊就诊的826例患者的临床资料做回顾性分析。结果示其发病时间主要在青少年期；有阳性家族史者占20．6％（170例），一、二级亲属共患率分别为44．1％（75例）和41．2％（70例），高于三级亲属；家族史阳性患者的平均发病年龄（25±16）岁，早于家族史阴性患者[（28±17）岁]，两者差异有统计学意义（t=1．97，P〈0．05）。合并自身免疫性疾病的患者67例，占8．1％；儿童白癜风患者比其他年龄患者更易发生同形反应和出现晕痣（P〈0．05）。

Clinical analysis on 826 cases of vitiligo

We retrospectively reviewed the clinical data of 826 cases with vitiligo treated in Beijing Hospital from 1998 to 2008. Most of patients present vitiligo in early age;20. 6% patients had positive family history. There were 44. 12 %, 41.18% and 10. 00 % of patients with vitiligo in their first, second and third degree relatives, respectively. Patients with family history had an earlier onset than those without a family history ( t = 1.97, P < 0. 05 ). Vitiligo vulgaris was found in 91.40 % patients. The most common affected site was head and face (31.5%) ;8. 1% of the patients was associated with other autoimmune diseases, including thyroid diseases, diabetes. There were more females than males in patients aged below 14. The child patients were more likely to present with Koebner' sign and halo nevus than the elder ones (P<0.05).