| Clinical experience with kidney transplantation in patients older than 65 years |
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| 引用本文： | 于立新 邓文锋 叶桂荣 苗芸 姚冰. Clinical experience with kidney transplantation in patients older than 65 years[J]. 中国人民解放军军医大学学报, 2002, 17(4): 281-284 |
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| 作者姓名： | 于立新 邓文锋 叶桂荣 苗芸 姚冰 |
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| 作者单位： | DepartmentofKidneyTransplantation,NanfangHospital,FirstMilitaryMedicalUniversity,Guangzhou510515,China |
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| 摘 要： | Objective: To explore the peculiarities of kidney transplantation in elderly patients and define the perioperative managements. Methods: The clinical data of kidney transplantation in 29 patients older than 65 years were reviewed, the eldest being 84 years old and the mean age 68.1 years. Results : Four episodes of a-cute rejection (13.80%) were encountered. FK506 toxicity occurred in one case (3. 40%) and lung infection in another (3.40%), who (along with the former 4 patients) all were cured subsequently. In one case, the kidney graft was removed for thrombogenesis of the renal artery. The 1- and 3-year patients/grafts survival of 100% and 96. 5% respectively was achieved, with the longest survival exceeding 5 years. Conclusions: Old age was not the absolute contraindication for kidney transplantation. Strict observance of the indications of kidney transplantation and donor selection with well-matched tissue-typing are crucial in elderly patients. Adequate application of immunosuppressants and effective long-term follow-up are also major factors for long-term allograft survival.
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| 关 键 词： | 肾移植 临床经验 同种异体移植 影响因素 |
Clinical experience with kidney transplantation in patients older than 65 years |
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| YU Li-xin,LIU Xiao-you,DENG Wen-feng,YE Gui-rong,MIAO Yun,YAO Bing. Clinical experience with kidney transplantation in patients older than 65 years[J]. Journal of Medical Colleges of PLA(China), 2002, 17(4): 281-284 |
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| Authors: | YU Li-xin LIU Xiao-you DENG Wen-feng YE Gui-rong MIAO Yun YAO Bing |
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| Abstract: | Objective: To explore the peculiarities of kidney transplantation in elderly patients and define the perioperative managements. Methods: The clinical data of kidney transplantation in 29 patients older than 65 years were reviewed, the eldest being 84 years old and the mean age 68.1 years. Results: Four episodes of a-cute rejection (13. 80%) were encountered. FK506 toxicity occurred in one case (3. 40%) and lung infection in another (3. 40%), who (along with the former 4 patients) all were cured subsequently. In one case, the kidney graft was removed for thrombogenesis of the renal artery. The 1- and 3-year patients/grafts survival of 100% and 96. 5% respectively was achieved, with the longest survival exceeding 5 years. Conclusions; Old age was not the absolute contraindication for kidney transplantation. Strict observance of the indications of kidney transplantation and donor selection with well-matched tissue-typing are crucial in elderly patients. Adequate application of immunosuppressants and effective long-term follow-up are also major factors for long-term allograft survival. |
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| Keywords: | kidney transplantation elderly patients graft survival |
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