In vitro antifungal susceptibility of Cryptococcus gattii |
| |
| Authors: | Trilles Luciana Fernández-Torres Belkys Lazéra Márcia dos Santos Wanke Bodo Guarro Josep |
| |
| Institution: | Serviçio de Micología Médica, Instituto de Pesquisa Clínica Evandro Chagas, FIOCRUZ, Rio de Janeiro, Brazil,1. Unitat de Microbiologia, Facultat de Medicina i Ciències de la Salut, Universitat Rovira i Virgili, Reus, Spain2. |
| |
| Abstract: | We have determined the in vitro susceptibilities of 57 strains of Cryptococcus gattii to nine antifungal agents and have compared the MICs for these strains with those for C. neoformans. MICs were determined by a microdilution reference method. Albaconazole and ravuconazole (MICs of 0.04 and 0.05 microg/ml, respectively) showed the best activities. Micafungin showed no activity (MIC of >128 microg/ml). In general, C. gattii was less susceptible than C. neoformans to all drugs tested, with the exception of amphotericin B and flucytosine. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
