| 角膜碱烧伤自由基清除剂治疗的实验研究 |
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| 引用本文： | 马蕾,王晶.角膜碱烧伤自由基清除剂治疗的实验研究[J].山西医药杂志,1998,27(2):116-117. |
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| 作者姓名： | 马蕾 王晶 |
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| 作者单位： | 山西医科大学第二医院，山西省眼科医院 |
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| 摘 要： | 探讨角膜碱烧伤后自由基清除剂治疗机制。将动物分成对照组、ＳＯＤ组、ＣＡＴ组及ＳＯＤ和ＣＡＴ联合治疗组，进行疗效观察。ＳＯＤ与ＣＡＴ联合组角膜溃疡发生率明显降低，与对照组相比差异显著（Ｐ＜０．０１）。角膜碱烧伤涉及自由基损伤机制，ＳＯＤ与ＣＡＴ联合治疗是从不同方面抑制自由基产生，证实采用自由基拮抗剂治疗碱烧伤是有意义的。
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| 关 键 词： | 角膜碱烧伤 超氧化物歧化酶 过氧化氢酶 联合治疗 |
AN EXPERIMENTAL STUDY ON ALKALI BURNS OF CORNEA TREATED WITH RADICAL SCAVENGERS |
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| Abstract: | Evaluate the usage of radical scavengers in alkali burns of cornea.Rabbits were divided into 4 groups:SOD,CAT,SOD CAT combined,and control.SOD CAT combined group has a lower level of corneal ulcer as compared with that of control group (P<001).Using SOD CAT to treat alkali burns of cornea has a significant effect,for they are the two main scavengers of free radicals in cornea. |
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| Keywords: | alkali burns of cornea superoxide dismutase catalase combined treatment |
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