心血管病患者血标本检验前凝血、溶血原因分析及对策

目的通过调查并分析心血管病患者血标本实验室分析前凝血、溶血原因，采取预防血标本凝血、溶血的采集方法，减少凝血、溶血发生。方法选取心血管病患者的血标本随机分为对照组7396份和实验组7334份，对照组血标本按照以往习惯采集及运送，实验组对血标本采集、标本运送、实验室传输等环节进行统一标化，分别记录对照组与实验组血标本的凝血、溶血原因、数量及种类，比较两组血标本不合格率及凝血、溶血不合格率。结果实验组标本不合格率为0．21％，低于对照组的0．82％，差异具有统计学意义（X^2=27．599，P〈0．01）；实验组标本凝血、溶血不合格率为0．18％显著低于对照组的0．65％，差异有统计学意义（X^2=19．923，P〈0．01）。结论加强对血标本检验前质量控制可有效减少不合格标本中的凝血、溶血标本数量，从而提高血标本质量，为临床疾病的诊断提供可靠、准确的科学依据。

Causes and strategies to deal with the coagulation and hemolysis of blood samples of cardiovascular disease patients before examination

Objective To study the causes of coagulation and hemolysis of blood samples collected from cardiovascular disease patients and the method to prevent its happening in order to reduce the numbers of coagulation and hemolysis samples. Methods All the blood samples of cardiovascular disease patients were randomly divided into control group（ n = 7396）and experimental group （n = 7334 ）. Control group was collected and transported according to the traditional methods, while the experimental group adopted standard control in sample collecting, transporting, laboratory transmission. Causes of the blood sample coagulation and hemolysis in two groups were observed. Results Unqualified blood samples ratio of experimental group was 0. 21% significantly lower than 0.82% that of the control group （X2 = 27. 599 ,P 〈 0.01 ）. The ratio of coagulation and hemolysis of experimental group was 0. 18%, and that of control group was 0.65%, and the difference was statistically significant （X2 = 19. 923, P 〈 0.01 ）. Conclusions Quality control of each procedure in the blood sample before examination can effectively reduce the number of unqualified blood coagulation and hemolysis and improve the quality of overall blood samples, and further provide reliable and accurate scientific evidence for disease diagnosis.