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Hepatic lipogranulomas in patients with chronic liver disease: association with hepatitis C and fatty liver disease
Authors:Zhu Hongfa  Bodenheimer Henry C  Clain David J  Min Albert D  Theise Neil D
Affiliation:Department of Pathology, Mount Sinai School of Medicine, New York, NY 10029, USA. hongfa.zhu@mountsinai.org
Abstract:AIM: To study the significance and clinical implication of hepatic lipogranuloma in chronic liver diseases, including fatty liver disease and hepatitis C. METHODS: A total of 376 sequential, archival liver biopsy specimens were reviewed. Lipogranuloma, steatosis and steato-fibrosis were evaluated with combined hematoxylin and eosin and Masson’s trichrome staining. RESULTS: Fifty-eight (15.4%) patients had lipogranuloma, including 46 patients with hepatitis C, 14 patients with fatty liver disease, and 5 pati...
Keywords:Lipogranuloma   Hepatitis C   Fatty liver disease   Steatosis   Steato-fibrosis
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