骨肉瘤患者焦虑和抑郁情绪及影响因素

目的了解住院骨肉瘤患者焦虑、抑郁情绪的发生率，并分析其焦虑、抑郁情绪的影响因素。方法采用焦虑自测量表（sAs）和抑郁自测量表（sDs）对94例骨肉瘤住院患者进行焦虑、抑郁情况测评，并分析其影响因素的调查。结果94例骨肉瘤患者焦虑和抑郁情绪的发生率分别为27．7％和44．7％。焦虑自评量表及抑郁自评量表总标准分分别为（44．95±11．11）和（50．22±12．40），均明显高于国内常模（33．80±5．90），（41．85±10．57）分，差异有统计学意义（t分别为6．878，4．629；P〈O．01）；Logistic多因素回归分析表明性别、疾病分期及文化水平是骨肉瘤患者抑郁和焦虑情绪的危险因素。结论骨肉瘤患者易出现焦虑、抑郁等心理问题，对于焦虑、抑郁危险因素暴露者应及早予以心理干预、社会支持和必要的药物治疗。

Investigation of anxiety and depression of osteosarcoma patients and its influence factors

Objective To study the incidence of anxiety and depression among patients with osteosarcoma so as to analyze its influencing factors. Methods Between January 2010 and December 2011, 94 hospitalized patients with osteosarcoma were investigated with self-rated anxiety scale （ Self-rating Anxiety Scale, SAS） and self-rated depression scale （Self-rating Depression Scale, SDS）, then analyzed the influencing factors. Results And the incidence of anxiety and depression was 27.7% and 44.7%, respectively. The total score of SAS and SDS of patients with osteosarcoma （44.95±11.11 ） and （50.22±12.40）, was significantly higher than that of the national norm （33.80±5.90）, （41.85±10.57） ;t = 6. 878,4. 629,respectively;P 〈 0. O1 ]. Logistic analysis showed that gender, disease stage and education were the influencing factors for anxiety and depression of patients with osteosarcoma. Conclusions Patients with osteosarcoma are easily have the mental problems of anxiety and depression, so psychological interventions, social support and necessary medicine treatment are necessary for osteosarcoma patients with anxiety and depression.