| 高血压脑出血病理生理机制研究进展 |
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| 引用本文： | 邓平,吴晓牧. 高血压脑出血病理生理机制研究进展[J]. 中华脑血管病杂志(电子版), 2010, 4(4): 19-26 |
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| 作者姓名： | 邓平 吴晓牧 |
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| 作者单位： | 江西省人民医院神经内科,南昌,330006 |
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| 基金项目： | 十一五国家科技支撑计划资助项目 |
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| 摘 要： | 高血压脑出血具有发病率高、致残率高、死亡率高的特点。其治疗近年来虽无突破性进展，但对血肿扩大、脑水肿等方面的研究较多。现就脑出血后脑组织的损伤机制、血肿扩大原因及其毒性作用以及出血半暗带、局部脑血流改变、炎症反应等在脑水肿形成中的作用等方面对脑出血的病理生理学机制研究的新进展作一综述。
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| 关 键 词： | 高血压脑出血 血肿 脑水肿 局部脑血流 炎症反应 |
The new progression of hypertensive cerebral hemorrhage pathophysiology |
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| DENG Ping,WU Xiao-mu. The new progression of hypertensive cerebral hemorrhage pathophysiology[J]. Chinese Journal of Cerebrovascular Diseases(Electronic Version), 2010, 4(4): 19-26 |
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| Authors: | DENG Ping WU Xiao-mu |
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| Affiliation: | . (Department of Neurology, the Jiangxi Provincial People＇ s Hospital, Nanchang 330006, China) |
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| Abstract: | Hypertensive cerebral hemorrhage has some features：high incidence rate, high mutilation rate and high mortality. There are not much breakthrough of treatment in recent years. Now the researchs of hypertensive cerebral hemorrhage have focusd on the enlargement of hematoma and the cerebral edema. This article reviews the mechanism of brain tissue injury after hemorrhage, the reasons of the enlargement of hematoma, the toxic effect of hematoma and the hemorrhage semidarkness area as well as the change of the local cerebral blood flow and inflammatory reaction. |
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| Keywords: | Hypertensive Cerebral Hemorrhage Hematoma cerebral edema Local cerebral blood flow Inflammatory reaction |
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