Islet-cell hyperplasia causing hyperinsulinemic hypoglycemia in an adult |
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Authors: | Yoshihide Ueda Kenji Kurihara Tsuyoshi Kondoh Toyotake Okanoue Tsutomu Chiba |
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Affiliation: | (1) Departments of Internal Medicine, Uwajima City Hospital, 1-1 Goten-machi, Uwajima, Ehime 798, Japan, JP;(2) Departments of Pathology, Uwajima City Hospital, 1-1 Goten-machi, Uwajima, Ehime 798, Japan, JP;(3) Departments of Surgery, Uwajima City Hospital, 1-1 Goten-machi, Uwajima, Ehime 798, Japan, JP;(4) Division of Gastroenterology and Hepatology, Department of Internal Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan, JP |
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Abstract: | We report a patient, a 23-year-old man, who had clinical and laboratory findings suggestive of insulinoma. Although imaging studies did not reveal any tumors in the pancreas, distal pancreatectomy was performed because the possibility of small insulinoma could not be completely excluded. Grossly, the surgically removed pancreas did not reveal any tumors. Microscopically, the pancreas exhibited islet cell hyperplasia and nesidioblastosis. To our knowledge, this is the first authentic reported case of islet-cell hyperplasia occurring in a Japanese adult. Received Mar. 4, 1997; accepted May 23, 1997 |
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Keywords: | : islet cell hyperplasia nesidioblastosis hyperinsulinemic hypoglycemia adult |
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