| 三种波形磁场对大鼠成骨细胞增殖与分化的影响 |
| |
| 引用本文： | 文峻,张晓军,张建保,屈学民. 三种波形磁场对大鼠成骨细胞增殖与分化的影响[J]. 中国医学物理学杂志, 2008, 25(3): 654-656 |
| |
| 作者姓名： | 文峻 张晓军 张建保 屈学民 |
| |
| 作者单位： | 1. 第四军医大学,生物医学工程系数理教研室,陕西,西安,710032
2. 西安交通大学,生物医学工程研究所,陕西,西安,710049 |
| |
| 摘 要： | 目的：研究不同波形磁场辐照，对离体大鼠成骨细胞增殖与分化的影响。方法：用矩形、三角形和正弦三种典型波形磁场辐照离体成骨细胞。结果：频率15Hz，幅值5mT，矩形磁场促进细胞增殖（P〈0．01），抑制细胞分化（P〈0．01）;正弦磁场抑制细胞增殖（P〈0．01），促进细胞分化（P〈0．01）；三角彤磁场对细胞增殖和分化的影响尤显著性差异．结论：除强度和频率窗外，还需考虑波形的影响。
|
| 关 键 词： | 成骨细胞 磁场 波形 增殖 分化 |
| 文章编号： | 1005-202X(2008)03-0654-03 |
| 修稿时间： | 2007-10-15 |
The Effect of Three Waveforms Magnetic Fields on Proliferation and Differentiation of Rat Osteoblasts |
| |
| WEN Jun,ZHANG Xiao-jun,ZHANG Jian-bao,QU Xue-min. The Effect of Three Waveforms Magnetic Fields on Proliferation and Differentiation of Rat Osteoblasts[J]. Chinese Journal of Medical Physics, 2008, 25(3): 654-656 |
| |
| Authors: | WEN Jun ZHANG Xiao-jun ZHANG Jian-bao QU Xue-min |
| |
| Affiliation: | WEN Jun, ZHANG Xiao-jun, ZHANG Jian-bao, QU Xue-min (1.Department of Mathematics and Physics, Fourth Military Medical University, Xi＇an Shaanxi 710032, China; 2.Institute of Biomedical Engineer, Xi＇an Jiaotong University, Xi＇an Shaanxi 710048, China) |
| |
| Abstract: | Objective： To study the effects on proliferation and differentiation of rat osteoblasts exposed to different waveform magnetic fields. Methods： The rat osteoblasts in vitro were exposed with three typical magnetic fields, the rectangular, the triangular and the sinusoidal. Results： With the frequency of 15 Hz and amplitude of 5 mT, the rectangular magnetic fields may increase cellular proliferation （P 〈 0.01） and decrease cellular differentiation （P 〈 0.01）, the sinusoidal decrease proliferation （P 〈 0.01） and increase differentiation（P 〈 0.01）, and than the triangular magnetic fields have no significantly effect on cellular proliferation and differentiation. Conclusions： Besides the windows of intensity and frequency, the effects of waveform should be considered. |
| |
| Keywords: | osteoblast magnetic field wave shape proliferation differentiation |
| 本文献已被 维普 万方数据 等数据库收录！ |
|
