生物材料的表面修饰对细胞黏附性的影响

细胞与生物材料相互作用过程中,细胞黏附是首先发生的生物学行为,对后续发生的迁徙、增殖和分化具有重要影响.因此,如何改善细胞在生物材料表面的黏附特性,自然成为目前组织工程研究的一项重要内容,目前较多采用的是对生物材料进行表面修饰的方法.就生物材料的表面修饰对细胞在生物材料上黏附的影响进展作一综述.

Effect of surface modification of biomaterials on cell adhesion

In the span of the interactions between cells and biomaterials, cell adhesion is the first biological behavior which has important effects on the following biological behaviors including cell migration, proliferation, and differentiation. So how to improve cell adhesion of biomaterials has become an important subject of tissue engi- neering. One of the popular methods is the surface modification of biomaterials. This article reviews the development of the research on the surface modification of biomaterials for improving cell adhesion.