Outbreak of pertussis on a college campus |
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Authors: | Craig Allen S Wright Seth W Edwards Kathryn M Greene John W Haynes MaryLou Dake Anthony D Schaffner William |
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Institution: | a Office of Workforce and Career Development, Centers for Disease Control and Prevention, Atlanta, Ga b Tennessee Department of Health, Nashville, Tenn c Department of Emergency Medicine, Vanderbilt University School of Medicine, Nashville, Tenn d Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tenn e Department of Preventive Medicine, Vanderbilt University School of Medicine, Nashville, Tenn. |
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Abstract: | BackgroundPertussis is increasing among adolescents and adults despite universal childhood vaccination. This investigation describes an outbreak of pertussis among undergraduate students and assesses the burden of cough illness on a college campus.MethodsStudents presenting with prolonged cough were evaluated with culture, polymerase chain reaction (PCR), and serology. An e-mail survey was performed to determine the burden of cough illness on campus.ResultsThirty-seven undergraduates were evaluated. Their mean duration of cough was 28 days. No student had cultures positive for B. pertussis; one was PCR positive. Ten (27%) had serologic values consistent with acute pertussis infection. The e-mail survey was returned by 225/500 (45%) students. Of these, 66 (29%; 95% confidence interval CI], 23%-36%) reported a cough of 2 weeks or longer duration during the fall semester. A conservative estimate showed that the campus-wide incidence of a cough illness meeting the Centers for Disease Control and Prevention case definition for pertussis was 13% (95% CI, 10%-16%) during the fall semester.ConclusionsAdolescents and young adults are susceptible to pertussis infection. This study demonstrates that there was a substantial rate of pertussis infection during an outbreak on a college campus. Our findings support the routine use of the acellular pertussis vaccine in adolescents and adults. |
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Keywords: | Bordetella pertussis College health Respiratory tract infections Whooping cough |
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