Revascularization with and without Platelet-rich Plasma in Nonvital,Immature, Anterior Teeth: A Pilot Clinical Study |
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Authors: | Ganesh JadhavNaseem Shah MDS Ajay Logani MDS |
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Affiliation: | Department of Conservative Dentistry and Endodontics, Centre for Dental Education and Research, All India Institute of Medical Sciences, New Delhi, India |
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Abstract: | IntroductionThis study was conducted to evaluate and compare maturogenesis induced by revascularization with and without platelet-rich plasma (PRP).MethodsTwenty patients with nonvital, immature anterior teeth were randomly categorized into 2 groups. Subsequent to chemomechanical preparation, revascularization with and without PRP carried on a collagen sponge was induced in groups 1 and 2, respectively. The cases were followed up clinically and radiographically at 6- and 12-month intervals.ResultsClinically, all cases were asymptomatic with complete resolution of signs and symptoms. Radiographically, there was a marked difference in periapical healing, apical closure, and dentinal wall thickening in group 2 in comparison with group 1. However, root lengthening was comparable for both of the procedures.ConclusionsRevascularization is a conservative and an effective method for inducing maturogenesis in nonvital, immature teeth. Supplementations with PRP can potentially improve the desired biological outcome of this regenerative technique. |
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Keywords: | Immature teeth maturogenesis platelet-rich plasma revascularization |
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