| 补肾活血方联合西药治疗糖皮质激素相关性骨量丢失的临床观察 |
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| 引用本文： | 张娜,苏晓.补肾活血方联合西药治疗糖皮质激素相关性骨量丢失的临床观察[J].上海中医药杂志,2016,50(1):58-61. |
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| 作者姓名： | 张娜 苏晓 |
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| 作者单位： | 上海中医药大学附属市中医医院风湿科,上海,200071,上海中医药大学附属市中医医院风湿科,上海,200071 |
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| 基金项目： | 上海市卫计委第三批上海市中医临床优势专科项目(ZYSNXD-YL-YSZK) |
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| 摘 要： | 目的观察补肾活血方联合西药治疗糖皮质激素相关性骨量丢失的临床疗效。方法将60例糖皮质激素相关性骨量丢失患者随机分为治疗组和对照组,每组30例。对照组予阿仑磷酸钠VitD_3片+碳酸钙D_3片,治疗组在对照组治疗基础上加用补肾活血方。两组疗程均为6个月,观察比较疼痛VAS评分、骨密度及骨代谢相关指标的变化情况。结果 1治疗前后组内比较,两组疼痛VAS评分差异有统计学意义(P0.05);组间治疗前后疼痛VAS评分差值比较,差异有统计学意义(P0.05)。2治疗前后组内比较,两组腰椎及双髋平均骨密度水平差异均有统计学意义(P0.05);组间治疗后比较,腰椎及双髋平均骨密度水平差异有统计学意义(P0.05)。3治疗前后组内比较,治疗组BGP、β-CTx、PTH、IL-6水平差异有统计学意义(P0.05),对照组β-CTx、PTH、IL-6水平差异有统计学意义(P0.05);组间治疗后比较,BGP、β-CTx及IL-6水平差异有统计学意义(P0.05)。结论补肾活血方联合西药治疗糖皮质激素相关性骨量丢失的疗效满意。
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| 关 键 词： | 糖皮质激素 骨量减少 骨质疏松 补肾活血 骨密度 骨代谢 |
| 收稿时间： | 2015/10/8 0:00:00 |
Clinical effect of the treatment of glucocorticoid related osteoporosis with the method of invigorating the kidney and promoting blood circulation combined with western medicine |
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| ZHANG Na and SU Xiao.Clinical effect of the treatment of glucocorticoid related osteoporosis with the method of invigorating the kidney and promoting blood circulation combined with western medicine[J].Shanghai Journal of Traditional Chinese Medicine,2016,50(1):58-61. |
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| Authors: | ZHANG Na and SU Xiao |
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| Institution: | Rheumtism Department, Shanghai Hospital of Traditional Chinese Medicine Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, 200071 and Rheumtism Department, Shanghai Hospital of Traditional Chinese Medicine Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, 200071 |
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