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结核抗体检测在结核病诊断中的意义
引用本文:王洪建,张玉库. 结核抗体检测在结核病诊断中的意义[J]. 中国基层医药, 2009, 16(10): 1758-1759. DOI: 10.3760/cma.j.issn.1008-6706.2009.10.017
作者姓名:王洪建  张玉库
作者单位:胶南市结核病防治所肺科,山东省胶南,266400
摘    要:目的探讨结核抗体(TB-Ab)检测在结核病诊断中的意义。方法对564例患者进行血清或胸(腹)水TB—Ab检测,其中活动性结核患者508例,非结核患者56例。结果活动性结核患者中,涂阳肺结核TB—Ab阳性率为70.8%;涂阴结核并胸水32例,腹水4例,腹水或胸水TB-Ab(阳性率为44.4%,另424例涂阴结核TB-Ab阳性168例,阳性率39.6%,活动性结核TB-Ab总阳性率约42.9%。非结核患者假阳性率为10.7%。结核患者与非结核患者TB-Ab检测有显著差异(X^2=22.65,P〈0.01)。结论TB-Ab检测对活动性结核的诊断有价值,但敏感性较低,可作为结核病的快速辅助诊断手段,但尚须临床进一步研究。

关 键 词:结核  抗体  细菌

The clinical value of tuberculosis antibody in diagnosis of tuberculosis
WANG Hong-jian,ZHANG Yu-ku. The clinical value of tuberculosis antibody in diagnosis of tuberculosis[J]. Chinese Journal of Primary Medicine and Pharmacy, 2009, 16(10): 1758-1759. DOI: 10.3760/cma.j.issn.1008-6706.2009.10.017
Authors:WANG Hong-jian  ZHANG Yu-ku
Affiliation:(Department of Pulmonary Tuberculosis ,Jiaonan tuberculosis conffolinstitute ,Jiaonan 266400, China)
Abstract:Objective To evaluate the diagnostic value of tuberculosis antibody. Methods 564 patients re-ceived detection of serum,in which,508 cases suffered from active tuberculosis(TB) and 56 cases suffered from non-active TB. Results 508 cases with active TB received detection AB-Ab in serum, 48 cases were bacteriological smear positive cases, the rate of serum TB-Ab positive cases was 70.8% (34/48), the rate of pleural effusion or ascites TB-Ab positive cases was 44.4% (16/36), the rate of serum TB-Ab positive cases in another 424 cases with bacteriologi-cal smear negative TB was 39.6% (168/424). There was significant difference between active TB group and non-ac-tive TB group(χ2= 22.65, P<0.01). Conclusion It is useful for diagnosis of active TB by detecting TB-Ab. It may be a rapid auxilliary diagnostic way in TB diagnosis.
Keywords:Tuberculosis  Antiboies,bacterial
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