Interactions gènes–environnement au cours de la bronchopneumopathie chronique obstructive et l'asthme. Relations avec la composition corporelle

Non-reversible pulmonary obstructive pulmonary diseases as COPD or reversible as asthma are mainly environmental driven diseases. In this context, genes–environment interplays through epigenetics play a role in body composition, the level of oxidant stress and the risk to develop an obstructive bronchial pattern. In this way, they are environmental and genetic factors with pleiotropic effects that might explain the close relationships between body composition and respiratory health.