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Chemical induction of ovarian epithelial carcinoma in mice |
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| Authors: | Allan J. Jacobs Gary L. Curtis James R. Newland Richard B. Wilson Wayne L. Ryan |
| Affiliation: | 1. Departments of Obstetrics and Gynecology, and Laboratory Medicine, University of Nebraska Medical Center, 42nd and Dewey Avenue, Omaha, Nebraska 68105 U.S.A.;2. Departments of Biochemistry, and Pathology and Laboratory Medicine, University of Nebraska Medical Center, 42nd and Dewey Avenue, Omaha, Nebraska 68105 U.S.A. |
| Abstract: | Murine ovaries were treated with silk sutures saturated with a solution of 7,12-dimethylbenz(a)anthracene in beeswax. One of 35 animals developed an epithelial carcinoma. This tumor was not successfully transplanted into young animals. |
| Keywords: | To whom reprint requests should be addressed. |
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