The International Study of Asthma and Allergies in Childhood (ISAAC) Phase Three: A global synthesis |
| |
| Authors: | J. Mallol J. Crane E. von Mutius J. Odhiambo U. Keil A. Stewart |
| |
| Affiliation: | 1. The Hospital for Sick Children, 555 University Avenue, Toronto, ON M5G 1X8, Canada;2. Department of Pediatrics, University of Toronto, Canada;3. University of California, Berkeley, 50 University Hall MC7360, Mail Drop Suite 710, Geographic Information Health and Exposure Science Laboratory (GIS HEAL), School of Public Health, Berkeley, CA 94720-7360, USA;4. Environment Canada, Air Quality Research Division, 4905 Dufferin St., Toronto, ON M3H 5T4, Canada;5. Dalla Lana School of Public Health, University of Toronto, Canada;6. Public Health Agency of Canada, Maternal and Infant Health Section, 200 Églantine Dr., 1910C, Ottawa, ON K1A 0K9, Canada;7. Carleton University, Department of Chemistry, College of Natural Sciences, 228 Steacie Building, Ottawa, ON K1S 5B6, Canada;8. Department of Clinical Epidemiology and Biostatistics, McMaster University, CRL, Room 233, 1280 Main Street West, Hamilton, ON L8S 4K1, Canada;9. Health Canada, Population Studies Division, 445-757 West Hastings Street, Federal Tower, Vancouver, BC V6C 1A1, Canada |
| |
| Abstract: | This ISAAC Phase Three synthesis provides summarised information on the main findings of the study, regional tables and figures related to the prevalence and severity of current symptoms of asthma, rhinoconjunctivitis and eczema in the main regions of the world. The large number of surveyed children (≈1,200,000), the large number of centres (233) and countries (98) that participated in ISAAC Phase Three makes this study the most comprehensive survey of these diseases ever undertaken. Globally, the prevalence for current asthma, rhinoconjunctivitis and eczema in the 13–14-year age group was 14.1%, 14.6% and 7.3%, respectively. In the 6–7-year age group the prevalence for current asthma, rhinoconjunctivitis and eczema was 11.7%, 8.5% and 7.9%, respectively. The study shows a wide variability in the prevalence and severity of asthma, rhinoconjunctivitis and eczema which occurs not just between regions and countries but between centres in the same country and centres in the same city. This study definitively establishes that the prevalence of those diseases can be very high in non-affluent centres with low socioeconomic conditions. The large variability also suggests a crucial role of local environment characteristics to determine the differences in prevalence between one place and another. Thus, ISAAC Phase Three has provided a large body of epidemiological information on asthma, rhinoconjunctivitis and eczema in childhood from contrasting environments which is expected to yield new clues about the aetiology of those conditions and reasons for their marked global variability. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
