| CTRP家族在代谢相关性疾病中的作用 |
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| 引用本文： | 杜金秋,张慧娟.CTRP家族在代谢相关性疾病中的作用[J].国际内分泌代谢杂志,2021,41(1). |
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| 作者姓名： | 杜金秋 张慧娟 |
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| 作者单位： | 哈尔滨医科大学附属第一医院内分泌科 150000 |
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| 基金项目： | 黑龙江省自然科学基金(H2016040)。 |
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| 摘 要： | 补体C1q/肿瘤坏死因子相关蛋白(complement-C1q/tumor necrosis factor-related protein,CTRP)家族是一类主要由脂肪组织分泌的脂肪因子超家族,结构特征相似,具有抗炎、胰岛素增敏、调节代谢和免疫等生物学功能。目前已经发现的CTRP家族成员包括CTRP1~15。研究发现CTRP家族与代谢相关疾病如糖尿病、肥胖、冠心病等密切相关。
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| 关 键 词： | 补体C1q/肿瘤坏死因子相关蛋白 代谢相关性疾病 胰岛素抵抗 |
Effects of CTRP family on metabolism-related diseases |
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| Du Jinqiu,Zhang Huijuan.Effects of CTRP family on metabolism-related diseases[J].International JOurnal of Endocrinology and Metabolism,2021,41(1). |
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| Authors: | Du Jinqiu Zhang Huijuan |
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| Institution: | (Department of Endocrinology,the First Affiliated Hospital of Harbin Medical University,Harbin 150000,China) |
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| Abstract: | Complement-C1q/tumor necrosis factor-related protein(CTRP)family is a superfamilyof aliphatic factors secreted mainly by adipose tissue with similar structural characteristics,and its biologicalfunctions are mainly related to anti-inflammation,insulin sensitization,metabolism and immunity.The CTRP family members including CTRP1-15 have been discovered.Studies have found that the CTRP familyis closely related to metabolism-related diseases such as diabetes mellitus,obesity and coronary heartdisease,etc. |
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| Keywords: | Complement-C1q/tumor necrosis factor-related protein Metabolism-related diseases Insulin resistance |
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