呋塞米联合贝那普利治疗慢性肺源性心脏病心力衰竭患者的效果

目的:观察呋塞米联合贝那普利治疗慢性肺源性心脏病(简称肺心病)心力衰竭患者的效果。方法:选取120例慢性肺心病心力衰竭患者作为研究对象,依据随机数字表法分为对照组和研究组各60例。对照组采用呋塞米治疗,研究组采用呋塞米联合贝那普利治疗。比较两组治疗效果、心功能指标水平、动脉血气指标水平和不良反应发生率。结果:研究组治疗总有效率为96.67%(58/60),显著高于对照组的85.00%(51/60),差异有统计学意义(P<0.05)。治疗后,两组左室射血分数、舒张早期三尖瓣环运动峰值速度、动脉血氧分压水平均高于治疗前,且研究组高于对照组,差异有统计学意义(P<0.05);两组舒张晚期三尖瓣环运动峰值速度、动脉血二氧化碳分压水平均低于治疗前,且研究组低于对照组,差异有统计学意义(P<0.05)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:呋塞米联合贝那普利治疗慢性肺心病心力衰竭患者可提高治疗总有效率,改善心功能指标水平和动脉血气指标水平,优于单纯呋塞米治疗效果。

Effects of Furosemide combined with Benazepril in treatment of patients with chronicpulmonary heart disease and heart failure

Objective:To explore effects of Furosemide combined with Benazepril in treatment of patients with chronic pulmonary heart disease and heart failure.Methods:120 patients with chronic pulmonary heart disease and heart failure were selected as the research objects,and were divided into control group and study group according to the random number table method,60 cases in each group.The control group was treated with Furosemide,while the study group was treated with Furosemide combined with Benazepril.The treatment effects,heart function index level,arterial blood gas index levels and incidence of adverse reactions were compared between the two groups.Results:The total effective rate of treatment in the study group was 96.67%(58/60),which was significantly higher than 85.00%(51/60)in the control group,and the difference was statistically significant(P<0.05).After the treatment,the levels of left ventricular ejection fraction,Ve and arterial partial pressure of oxygen in the two groups were higher than those before the treatment;those of the observation group were higher than those of the control group;and the differences were statistically significant(P<0.05).After the treatment,the Va and arterial partial pressure of carbon dioxide levels of the two groups were lower than those before the treatment;those of the observation group were lower than those of the control group;and the differences were statistically significant(P<0.05).However,there was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusions:Furosemide combined with Benazepril in the treatment of the patients with chronic pulmonary heart disease and heart failure can increase the total effective rate of treatment,improve the levels of heart function indexes and arterial blood gas indicators.Moreover,it is superior to single Furosemide.