Common features of anaphylaxis in children |
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| Authors: | M Serbes D Can F Atlihan I Günay S Asilsoy S Altinöz |
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| Institution: | 1. Sección de Alergia y Inmunología Clínica, Hospital Sant Joan de Déu, Esplugues, Universitat de Barcelona, Barcelona, Spain;2. Alergia Infantil, Servicio de Pediatría, Clinica de Jerez, Spain;3. Unidad de Neumología y Alergia Pediátricas, Hospital de Sabadell, Corporació Sanitària Universitària Parc Taulí, Spain;4. Sección de Alergia Pediátrica, Hospital Universitario Virgen Arrixaca, Murcia, Spain;5. Alergia Infantil, Servicio de Pediatria, H. El Escorial, Madrid, Spain;6. Servicio de Alergología, Complejo Hospitalario de Navarra, Spain;7. Unidad de Alergia y Neumología Pediátrica, Hospital Universitario Virgen de las Nieves de Granada, Spain;1. Pneumology Unit, Cuasso al Monte, Macchi Hospital Foundation, Varese, Italy;2. Department of Ecosystem and Public Health, Faculty of Veterinary Medicine, University of Calgary, Alberta, Canada;3. Lofarma SpA, Medical Department, Milano, Italy;4. Allergy and Respiratory Diseases Clinic, Dept of Internal Medicine, University of Genoa, Italy;1. Center for Endoscopic Research and Therapeutics, The University of Chicago Medicine and Biological Sciences, Chicago, Illinois, USA;3. Department of Medicine, Section of Infectious Diseases & Global Health, The University of Chicago Medicine and Biological Sciences, Chicago, Illinois, USA;2. National Cancer Institute of Mexico, Mexico City, Mexico;1. Institute of Chemical Technology and Engineering, Poznan University of Technology, M. Sk?odowskiej-Curie 2, 60-965 Poznan, Poland;2. Institute of Chemistry and Technical Electrochemistry, Poznan University of Technology, Piotrowo 3, 60-965 Poznan, Poland;1. Key Laboratory of Environment Correlative Dietology, Huazhong Agricultural University, Ministry of Education, Wuhan 430070, Hubei, People’s Republic of China;2. College of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, People’s Republic of China;3. Institute of Bioengineering, Department of Chemical and Biological Engineering, Zhejiang University, Hangzhou 310027, People’s Republic of China;1. Clínica Servet, Santiago de Chile, Chile;2. Fundación de Aerobiología Medio Ambiente y Salud, Santiago de Chile, Chile;3. Universidad Católica Maule, Talca, Chile;4. Instituto Biología Vegetal y Biotecnología, Universidad de Talca, Talca, Chile;5. Facultad de Ciencias de la Salud, Universidad de Talca, Talca, Chile;6. Servicio de Medicina Interna, Hospital Regional de Talca, Talca, Chile;7. Sección de Inmunología, Alergía y VIH, Servicio de Medicina, Hospital Clínico, Universidad de Chile, Santiago de Chile, Chile;8. Grupo de Alergología Clínica y Experimental (GACE), Grupo Académico de Epidemiología Clínica (GRAEPIC), Universidad de Antioquia, Medellín, Colombia |
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| Abstract: | ObjectiveWe aimed to establish the characteristics of anaphylaxis in childhood.MethodsForty-four patients who had experienced anaphylaxis in a period of 10 years (from 1999 to 2009), were included in the study. Parameters analysed were age, gender, concomitant allergic disease, trigger, setting, clinical symptoms, treatment, prognosis and prophylaxis.ResultsThe total numbers of anaphylaxis cases were 44 in a ten-year period. The ages of patients ranged from 3 to 14 years (11.50 ± 3.87 years) and the majority were male. 33 of the patients (75%) had a concomitant allergic disease. The trigger was determined in 93.2% of the cases, being most frequent: food (27.3%), and SIT (25%), followed by bee sting, medications and others. Respiratory (95.5%), dermatological (90.9%), cardiovascular (20.5%), neuropsychiatric (25%), and gastrointestinal (11.4%) symptoms were seen most frequently. For anaphylaxis triggered by food, the duration of anaphylactic episode was significantly longer (p < 0.05). No biphasic reaction was observed during these attacks. Of our patients, only one developed respiratory failure and cardiac arrest due to SIT, and intensive care support was required.DiscussionAs a trigger for anaphylaxis, the frequency of SIT is so high that it cannot be described by the study group including patients who were followed up in an outpatient allergy clinic. |
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