晚期早产儿患病情况的回顾性分析

目的比较晚期早产儿、足月新生儿的发病例数以及多系统疾病患病率的差异,为今后晚期早产儿的临床研究和医疗提供依据。方法回顾性分析2009年7月至2011年4月新生儿病房收住的新生儿共1480例次,其中晚期早产儿232例,足月新生儿1129例,应用统计学方法对晚期早产儿与足月儿的患病率进行比较,寻找两组患儿在患病率以及呼吸系统疾病的治疗和病死率上是否存在差异。结果晚期早产儿中湿肺、喂养不耐受、低钙血症、新生儿呼吸窘迫综合征的患病率远高于足月新生儿,两组比较有显著性差异（P〈0.01）,在发生呼吸系统并发症时需要CPAP（持续气道正压通气）呼吸支持治疗的比例高于足月新生儿,有统计学差异（P〈0.01）。结论晚期早产儿多种疾病的患病率高于足月新生儿,应给予高度重视。

Retrospective analysis on morbidity of late-preterm infants

Objective To compare the differences of the case load and morbidity of various complications of late-preterm infants and full-term infants,and provide basis for future clinical research of late-preterm infants.Methods 1 480 neonatal records were reviewed from Jul 2009 to Apr 2011.There were totally 232 late-preterm and 1 129 full-term infants admitted during that time.Statistics method was used to contrast the morbidity of these two groups,and to find out weather there were differences of it,and the treatment for respiratory complications and case-fatality rate between the two groups.Results The morbidity of wet-lung disease,feeding intolerance,hypocalcemia and neonatal respiratory distress syndrome in late-preterm infant group was significantly higher than full-term infant group（P0.01）.The proportion of the usage of CPAP（continuous positive airway pressure） was also higher in late-preterm infants group when respiratory complications happened（P0.01）.Conclusion The morbidity of some complications in late-preterm infants is higher than full-term infants,and they are high risk population which should not be ignored.