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| 气相色谱法测定六神丸中麝香酮含量 | |
| 引用本文： | 吕霞,郭青,钟文英.气相色谱法测定六神丸中麝香酮含量[J].中国药业,2010,19(21):24-25. |
| 作者姓名： | 吕霞 郭青 钟文英 |
| 作者单位： | 1. 江苏联合职业技术学院连云港中医药分院,江苏,连云港,222006 2. 江苏省食品药品检验所,江苏,南京,210008 3. 中国药科大学,江苏,南京,210009 |
| 摘 要： | 目的建立测定六神丸中麝香酮含量的气相色谱法。方法样品用乙酸乙酯浸渍提取后进样,采用HP50＋石英毛细管色谱柱（30m×0.53mm,1μm）,以N2为载气,柱温165℃,进样口温度150℃,火焰离子化检测器温度190℃。结果麝香酮质量浓度在23.90～1195.00μg/mL范围内与峰面积线性关系良好（r=0.9997）,麝香酮的平均回收率为99.16%,RSD为1.04%（n=9）。结论气相色谱法简单、准确,可用于六神丸的质量控制。 |
| 关 键 词： | 气相色谱法 六神丸 麝香酮 含量测定 |
Determination of Muscone in Liushen Pills by GC |
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| Lu Xia,Guo Qing,Zhong Wenying.Determination of Muscone in Liushen Pills by GC[J].China Pharmaceuticals,2010,19(21):24-25. | |
| Authors: | Lu Xia Guo Qing Zhong Wenying |
| Institution: | 1.Lianyungang Traditional Chinese Medicine Branch,Jiangsu Union Technical Institute,Lianyungang,Jiangsu,China 222006;2.Jiangsu Provincial Institute for Food and Drug Control,Nanjing,Jiangsu,China 210008;3.China Pharmaceutical University,Nanjing,Jiangsu,China 210009) |
| Abstract: | Objective To develop a GC method for the determination of muscone in Liushen Pills.Methods The chromatographic separation was carried out on the capillary column（HP 50 ＋,30 m × 0.53 mm,1 μm）,FID as the detector,using nitrogen as carrier gas.The temperature of column,inlet and detector was set at 165 ℃,150 ℃ and 190 ℃,respectively.Results The good linear relationship was exhibited in the range of 23.90-1 195.00 μg /mL（r = 0.999 7）.The average recovery rate was 99.16%（RSD = 1.04%）.Conclusion This method is simple and reliable for the quality control of Liushen Pills. |
| Keywords: | GC Liushen Pill muscone content determination |
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