Adherence to treatment guidelines in the pharmacological management of chronic heart failure in an Australian population |
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Authors: | Yao Dao-Kuo Wang Le-Xin Curran Shane Ball Patrick |
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Institution: | 1. Department of Cardiology,Beijing Friendship Hospital,Capital Medical University,Beijing 100050,China; School of Biomedical Sciences and Centre for Inland Health,Charles Sturt University,Wagga Wagga,NSW 2678,Australia 2. School of Biomedical Sciences and Centre for Inland Health,Charles Sturt University,Wagga Wagga,NSW 2678,Australia 3. School of Biomedical Sciences and Centre for Inland Health,Charles Sturt University,Wagga Wagga,NSW 2678,Australia; Department of Emergency Medicine,Wagga Wagga Base Hospital and Rural Clinical School,University of New South Wales,Wagga Wagga,NSW 2650,Australia |
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Abstract: | Background To document the pharmacotherapy of chronic heart failure (CHF) and to evaluate the adherence to treatment guidelines in Australian population.Methods The pharmacological management of 677 patients (female 46.7%,75.5±11.6 years) with CHF was retrospectively analyzed.Results The use of angiotensin converting enzyme (ACE) inhibitors/angiotensin receptor blockers (ARB) and fl-blockers were 58.2%and 34.7%,respectively.Major reasons for non-use of ACE inhibitors/ARBs were hyperkalemia and elevated serum creatimne level.For patients who did not receive β-blockers,asthma and chronic obstructive pulmonary disease were the main contraindications.Treatment at or above target dosages for ACE inhibitors/ARBs and β-blockers was low for each medication (40.3% and 28.9%,respectively).Conclusions Evidenced-based medical therapies for heart failure were under used in a rural patient population.Further studies are required to develop processes to improve the optimal use of heart failure medications. |
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Keywords: | heart failure ACE inhibitors angiotensin receptor β-blockers prognosis |
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