99Tcm-Tetrofosmin显像对乳腺癌及腋窝淋巴结转移诊断价值评价

目的 评价^99Tc^m-Tetrofosmin乳腺显像对乳腺肿块及腋窝淋巴结性质的鉴别诊断价值。方法 采用前瞻性和盲法对51例原发性乳腺癌和43例乳腺良性肿块患者术前进行^99Tc^m-Tetrofosmin乳腺和腋窝淋巴结平面显像，以病理结果为“金标准”，评价该方法常规读片分析对病灶性质鉴别诊断的价值。结果 ^99Tc^m-Tetrofosmin乳腺平面显像对乳腺癌诊断的灵敏度为88．2％，特异性为88．4％，准确率为88．3％。对乳腺癌淋巴结转移灶诊断分别为53．9％，94．1％和69．8％。结论 ^99Tc^m-Tetrofosmin乳腺显像作为一种非创性和简便的方法，对乳腺肿块及腋窝淋巴节性质的鉴别诊断有较大的价值，采用断层显像并结合其他诊断方法，能为临床提供更准确的诊断信息。

Evaluation of 99Tcm-Tetrofosmin Imaging in Detection of Primary Breast Cancer and Axillary Lymph Node Metastasis

Objective To evaluate the usefulness of 99 Tc m-Tetrofosmin imaging in detection of both primary breast cancer (PBC) and axillary lymph node metastasis (ALNM).Methods Fifty-one patients with PBC and 43 with breast benign masses were examined using SPECT planar imaging before operation.Conventional SPECT film was interpreted by more than 2 physicians with blind method.The imaging results were analyzed according to histopathological diagnoses.Results The sensitivity,specificity and accuracy of planar imaging were 88.2%,88.4% and 88.3% for the detection of PBC,respectively.The sensitivity was 53.9% for detecting ALNM.Specificity and accuracy were 94.1% and 69.8%,respectively.Conclusion 99 Tc m-Tetrofosmin imaging was useful tool in detection of both PBC and ALNM.It plays complementary role in the detection of breast cancer in some patients.