贵州荔波布依族与水族人群ABO血型分布及基因频率调查

目的：了解贵州省荔波县布依族、水族人群ABO血型分布及基因频率。方法分别对贵州省荔波县布依族（726人）、水族（163人）3代以内无血缘关系的个体采用玻片快速凝集法进行ABO血型检测。结果荔波县布依族、水族群体ABO血型分布均符合Hardy-Weinberg平衡。布依族ABO血型的表型分布特征为O＞B＞A＞AB ，基因频率均为r＞q＞p （r＝0.6769、q＝0.1767、P＝0.1464），民族指数小于1（0.842）；水族ABO血型的表型分布特征为O＞ A＞B＞ AB ，基因频率为r＞ p＞ q（r＝0.5226、q＝0.1040、P＝0.1647），民族指数大于1（1.529）。结论贵州省荔波县布依族、水族的ABO血型分布与贵州省其他地区同一民族群体的分布规律一致。遗传距离分析提示ABO 血型分布存地区性和民族性差异。

An investigation on ABO blood type distribution and gene frequency of Buyi,Shui ethnic populations in Libo county of Guizhou province

Objective To understand the ABO blood type distribution of Buyi and Shui ethnic populations in Libo county of Guizhou province .Methods Totally 726 Buyi and 163 Shui individuals who were unrelated within three generations were detected ABO blood stype with glass-clotted method .Results The ABO blood type distributions in the Buyi and Shui ethnic populations both were in line with the Hardy-Weinberg equilibrium .The Buyi ethnic population ABO phenotypic distribution and gene frequen-cies were O>B>A>AB and r>q>p (r=0 .676 9 ,q=0 .176 7 ,P=0 .146 4) and the national index was 0 .842;while the Shui eth-nic population ABO phenotypic distribution and gene frequencies were O>A>B>AB and r>p>q(r=0 .522 6 ,q=0 .104 0 ,P=0 .164 7) and the national index was 1 .529 .Conclusion The Buyi and Shui ethnic populations′ABO blood type distribution in Libo county of Guizhou province is basically consistent with that of the same ethnic populations in other regions of Guizhou Province of the same ethnic groups .The genetic distance analysis prompts that the regional and ethnic differences exist in ABO blood type dis-tribution .