Synaptic plasticity and dynamic modulation of the postsynaptic membrane |
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| Authors: | Lüscher C Nicoll R A Malenka R C Muller D |
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| Affiliation: | Department of Pharmacology (APSIC), CMU, 1, Rue Michel-Servet, Université de Genève, 1211 Geneva 4, Switzerland. christian.luscher@medecine.unige.ch |
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| Abstract: | The biochemical composition of the postsynaptic membrane and the structure of dendritic spines may be rapidly modulated by synaptic activity. Here we review these findings, discuss their implications for long-term potentiation (LTP) and long-term depression (LTD) and propose a model of sequentially occurring expression mechanisms. |
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