抗抑郁护理在功能性便秘患者中的应用

目的：分析探讨抗抑郁护理在功能性便秘疾病患者中的临床价值和意义。方法选择海军总医院2010年12月-2012年12月90例功能性便秘患者按住院号随机均分为3组，A组患者采用常规护理，同时给予小剂量帕罗西汀；B组患者行抗抑郁护理；C组患者采用常规护理。分别于治疗前及干预后1，2周对各组患者抑郁自评量表（ SDS）、焦虑自评量表（ SAS）及药物不良反应进行统计学分析。结果3组间患者入院时平均SDS、SAS评分水平，差异均无统计学意义（ F分别为0．280，1．286；P＞0．05，LSD法两两比较分析均P＞0．05）。入院1周A、B组SDS、SAS评分略低于C组，差异均无统计学意义（F分别为1．927，1．286；P＞0．05，且LSD法两两比较分析均P＞0．05）；入院2周A、B组SDS、SAS评分明显低于C组，差异有统计学意义（F分别为16．337，17．733，P＜0．05，LSD法分析A、C组，B、C组间比较P＜0．05）。析因实验方差分析SDS、SAS改变与不同抗抑郁干预方式-时间因素均存在差异（ F分别为66．744，12．806；P＜0．01），且存在交互作用。同时A组患者药物不良反应率明显高于B、C组患者，差异有统计学意义（χ2＝12．857，P＜0．01）。结论抗抑郁护理能明显缓解功能性便秘患者的焦虑、抑郁情绪及临床症状评分，并可有效避免抗抑郁药物引起的不良反应，具有重要的护理价值，值得临床推广。

Application of antidepressant nursing in patients with functional constipation

Objective To investigate the clinical value and significance of antidepressant nursing in patients with functional constipation .Methods From December 2010 to December 2012 , 90 cases of functional＆amp;nbsp;constipation were randomly divided into three groups .Patients in group A were given routine nursing care and a small dose of paroxetine;patients in group B were treated with antidepressant; patients in group C were given routine nursing care .Before treatment , and after 1 week and 2 weeks of treatment , the Self Rating Depression Scale （ SDS） , the Self Rating Anxiety Scale （ SAS ） and adverse drug reactions were statistically analyzed . Results The scores of SDS and SAS among the three groups had no significant differences when patients first charged into the hospital （F=0.280, 1.286, respectively; P〉0.05 and LSD P〉0.05）.After 1 week of treatment, the SDS and SAS scores of group A and B were slightly lower than those in group C （ F=1.927, 1.286, respectively;P〉0.05 and LSD P〉0.05）, but there was no significant differences .After 2 weeks of treatment, the SDS and SAS scores of group A and B were significantly lower than those in group C （ F =16.337, 17.733, respectively; P 〈0.05 and LSD P 〈0.05 ）, indicating the existence of significant differences .Factorial analysis of variance results showed that the changes of SDS and SAS and the differences of antidepressant intervention method-time were different （F=66.744, 12.806, respectively;P〈0.01）, with an interaction.The incidence of adverse drug effect was significantly higher in group A than that in group B or group C （χ2 =12.857,P〈0.01）.Conclusions Antidepressant nursing can relieve anxiety and depression symptoms in patients with functional constipation , and can effectively avoid the adverse reaction induced by antidepressants , so it is worthy of the clinical promotion .